Parameter
| Biomarker | Aldosterone | Full name | Aldosterone | Molecular Type | Steroid hormones (protein derivatives) |
|---|---|---|---|---|---|
| Molecular Formula | / | Molecular Weight | 360.45 Da | Core Functional Dimensions | Diagnosis, susceptibility, prognosis, monitoring |
| Disease | hypertension | Disease Subtypes | / | ||
| Organ | Adrenal cortex | Test Sample / Technology Platform | Serum/plasma (ELISA, mass spectrometry, radioimmunoassay) | ||
| Pathobiological Mechanisms | Activated RAAS system, promote the renal sodium water retention, vascular smooth muscle contraction, induced myocardial and vascular fibrosis | ||||
| Clinical Availability Status | Clinically available (secondary hypertension diagnosis, treatment monitoring) | ||||
| Notes and Dynamics | It is a key driver of refractory hypertension. Aldosterone receptor antagonist (spironolactone, eplerenone) is the first-line treatment drug and is closely related to obesity-related hypertension | ||||