Parameter
| Biomarker | Leptin | Full name | Leptin | Molecular Type | Protein (fat factor) |
|---|---|---|---|---|---|
| Molecular Formula | / | Molecular Weight | 16 kDa | Core Functional Dimensions | Susceptibility, prognosis |
| Disease | hypertension | Disease Subtypes | / | ||
| Organ | Adipose tissue | Test Sample / Technology Platform | Serum/plasma (ELISA, immunoradiometric assay) | ||
| Pathobiological Mechanisms | Obesity related fat factor, directly stimulate the adrenal aldosterone secretion, activation of the sympathetic nerve, promote water retention of sodium | ||||
| Clinical Availability Status | Validation/clinical exploration: closely associated with obesity related hypertension, used for risk stratification | ||||
| Notes and Dynamics | There is common in patients with obesity leptin resistance, but its cardiovascular effects persist, is an important intervention targets for obesity related hypertension | ||||