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773

Parameter
Biomarker Adiponectin Full name Adiponectin Molecular Type Proteins (adipokines)
Molecular Formula / Molecular Weight 30 kDa Core Functional Dimensions Susceptibility, prognosis
Disease hypertension Disease Subtypes /
Organ Adipose tissue Test Sample / Technology Platform Serum/plasma (ELISA, mass spectrometry)
Pathobiological Mechanisms It has anti-inflammatory and anti-atherosclerotic effects, and reduced levels can exacerbate vascular endothelial dysfunction and increase blood pressure
Clinical Availability Status Study validation: negative correlation with hypertension, used to assess the risk of metabolism-related hypertension
Notes and Dynamics Adiponectin levels are significantly decreased in obese and insulin resistant patients, and supplementation of adiponectin analogues can improve vascular function in experimental hypertension

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This study was supported by the Scientific Research Innovation Capability Support Project for Young Faculty (SRICSPYF-ZY2025112), the Fundamental and Interdisciplinary Disciplines Breakthrough Plan of the Ministry of Education of China (JYB2025XDXM612)

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