Parameter
| Biomarker | cTnI/cTnT | Full name | Cardiac troponin I / Cardiac troponin T | Molecular Type | protein |
|---|---|---|---|---|---|
| Molecular Formula | / | Molecular Weight | cTnI: 24 kDa; cTnT: ~37 kDa | Core Functional Dimensions | Diagnosis, Prognosis |
| Disease | Coronary heart disease (CHD) | Disease Subtypes | / | ||
| Organ | Myocardium (cardiac muscle cells) | Test Sample / Technology Platform | Whole blood plasma (ECLIA and ELISA) | ||
| Pathobiological Mechanisms | Ischemic necrosis of the myocardium leads to rupture of cardiomyocytes and release of specific troponin into the blood. | ||||
| Clinical Availability Status | Clinical routine/guidelines recommend: acute myocardial infarction (AMI) in the diagnosis of gold standard, high-sensitivity detection can be early identification of myocardial injury | ||||
| Notes and Dynamics | Hs-cTn can realize AMI within 3 hours of symptom onset, rapid diagnostic core indicators is the emergency department, reduce missed diagnosis | ||||