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Parameter
Biomarker CK-MB Full name Creatine kinase MB isoenzyme Molecular Type Protein
Molecular Formula / Molecular Weight 86 kDa Core Functional Dimensions Diagnosis, assessment of the condition
Disease Coronary heart disease (CHD) Disease Subtypes /
Organ Myocardium, skeletal muscle (minor) Test Sample / Technology Platform Whole blood/plasma (immunoturbidimetry, mass spectrometry)
Pathobiological Mechanisms Enzymes released after myocardial injury, level changes reflect infarction range, also can evaluate reperfusion therapeutic effect
Clinical Availability Status Clinical routine/validation: auxiliary cTn diagnosis, supplementary assess the degree of myocardial injury, especially for reperfusion efficacy monitoring
Notes and Dynamics Percutaneous coronary intervention (PCI) after 12 hours of CK-MB level, can accurately predict the forward area of myocardial infarction (MI), guiding the follow-up treatment

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This study was supported by the Scientific Research Innovation Capability Support Project for Young Faculty (SRICSPYF-ZY2025112), the Fundamental and Interdisciplinary Disciplines Breakthrough Plan of the Ministry of Education of China (JYB2025XDXM612)

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