Parameter
| Biomarker | BNP/NT-proBNP | Full name | Brain natriuretic peptide / N-terminal pro-brain natriuretic peptide | Molecular Type | Peptides |
|---|---|---|---|---|---|
| Molecular Formula | / | Molecular Weight | BNP: 4 kDa; NT-proBNP: 10 kDa | Core Functional Dimensions | Prognosis, cardiac function evaluation |
| Disease | Coronary heart disease (CHD) | Disease Subtypes | / | ||
| Organ | Myocardium (ventricular cardiomyocytes) | Test Sample / Technology Platform | Whole blood plasma (immunofluorescence) | ||
| Pathobiological Mechanisms | Ventricular pressure load induced synthesis, reflect the degree of myocardial reconstruction and cardiac insufficiency severity | ||||
| Clinical Availability Status | Clinical routine: used for heart failure stratification and prognosis judgment, one of the core risk stratification indicators for ACS patients | ||||
| Notes and Dynamics | The stability of NT-proBNP is better than that of BNP, and its half-life is longer, which is more suitable for long-term follow-up monitoring of cardiac function changes | ||||