Parameter
| Biomarker | Lp-PLA2 | Full name | Lipoprotein-associated phospholipase A2 | Molecular Type | Protein |
|---|---|---|---|---|---|
| Molecular Formula | / | Molecular Weight | 45 kDa | Core Functional Dimensions | Susceptibility |
| Disease | Coronary heart disease (CHD) | Disease Subtypes | / | ||
| Organ | Liver, macrophages, platelets | Test Sample / Technology Platform | Plasma (ELISA) | ||
| Pathobiological Mechanisms | Hydrolysis, the oxidation of phospholipids in the arteries, the proinflammatory medium, accelerate the process of atherosclerosis, increase the risk of plaque rupture | ||||
| Clinical Availability Status | Validation/clinical exploration: specific reflect the inflammation of the blood vessel walls, is the key to predict plaque stability markers | ||||
| Notes and Dynamics | Different from systemic inflammation index, of atherosclerosis has specificity, is expected to be incorporated in the high-risk population screening for coronary heart disease system | ||||