Parameter
| Biomarker | Myoglobin (Mb) | Full name | Myoglobin (Mb) | Molecular Type | protein |
|---|---|---|---|---|---|
| Molecular Formula | / | Molecular Weight | 17 kDa | Core Functional Dimensions | Early diagnosis and rule out the diagnosis |
| Disease | Coronary heart disease (CHD) | Disease Subtypes | / | ||
| Organ | Myocardium, skeletal muscle | Test Sample / Technology Platform | Serum/plasma (ELISA, POCT, immune chromatography) | ||
| Pathobiological Mechanisms | 1 h is elevated, 4-12 h of peak, 24-48 h restoring baseline; Joint cTn or CK-MB make up for a lack of specificity, high patients avoid misdiagnosis of skeletal muscle injury | ||||
| Clinical Availability Status | Early clinical available (exclude diagnosis) : guidelines recommended for AMI exclude diagnosis within 6 h of stroke onset, negative predictive value (NPV) of more than 90%, emergency POCT platform is widely used | ||||
| Notes and Dynamics | 1 h is elevated, 4-12 h of peak, 24-48 h restoring baseline; Joint cTn or CK-MB make up for a lack of specificity, avoid misdiagnosis in patients with skeletal muscle injury | ||||