Parameter
| Biomarker | GPBB | Full name | Glycogen phosphorylase BB isoenzyme | Molecular Type | protein |
|---|---|---|---|---|---|
| Molecular Formula | / | Molecular Weight | 97 kDa | Core Functional Dimensions | Early Diagnosis |
| Disease | Coronary heart disease (CHD) | Disease Subtypes | / | ||
| Organ | Myocardium, brain | Test Sample / Technology Platform | Serum (ELISA, immune chromatography, chemiluminescence) | ||
| Pathobiological Mechanisms | Myocardial ischemia, activation glycogen decomposition energy, released into the bloodstream after cellular damage; Is a key enzyme glycogen metabolism, the myocardial specificity is higher | ||||
| Clinical Availability Status | Research validation: single-center studies confirmed that the onset of 1-4 h sensitivity is better than that of myoglobin, but not into the mainstream clinical guidelines, only in the center of the part of the cardiovascular specialist for difficult cases | ||||
| Notes and Dynamics | Ischemia, which release (before the cTn), 6-10 h up to the peak, 24 h recovery; And is associated with the degree of myocardial ischemia, can be used to evaluate the myocardial suppression "potential injury patients | ||||