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15

Parameter
Biomarker CLEC10A Full name C-Type Lectin Domain Family 10 Member A Molecular Type Nucleic acid (RNA)
Molecular Formula Molecular Weight Core Functional Dimensions Diagnosis (related to thrombocytopenia)
Disease Acute Myeloid Leukemia (AML) Disease Subtypes /
Organ Blood, bone marrow Test Sample / Technology Platform Bone marrow (RNA sequencing, qRT-PCR)
Pathobiological Mechanisms Participates in bone remodeling and immune-related pathways, associated with the interference of leukemia cells on platelet function
Clinical Availability Status Research verification: Incorporating low platelet count into AML prediction model.
Notes and Dynamics Provide a new perspective for understanding the pathophysiological mechanisms of low platelet AML.

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This study was supported by the Scientific Research Innovation Capability Support Project for Young Faculty (SRICSPYF-ZY2025112), the Fundamental and Interdisciplinary Disciplines Breakthrough Plan of the Ministry of Education of China (JYB2025XDXM612)

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