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17

Parameter
Biomarker FIBP Full name Fibroblast Growth Factor Binding Protein 1 Molecular Type Protein
Molecular Formula Molecular Weight Core Functional Dimensions Prognosis, immune infiltration-related
Disease Acute Myeloid Leukemia (AML) Disease Subtypes /
Organ Blood, bone marrow Test Sample / Technology Platform Bone marrow (RNA sequencing, qRT-PCR)
Pathobiological Mechanisms Participates in leukocyte migration, adhesion, and T-cell tolerance induction, and is associated with immune cell infiltration.
Clinical Availability Status Study validation: Significantly shortened overall survival in the high-expression group.
Notes and Dynamics Positively correlated with CD4, IL-10, and IL-2, providing a basis for combined immunotherapy.

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This study was supported by the Scientific Research Innovation Capability Support Project for Young Faculty (SRICSPYF-ZY2025112), the Fundamental and Interdisciplinary Disciplines Breakthrough Plan of the Ministry of Education of China (JYB2025XDXM612)

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