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18

Parameter
Biomarker TROAP Full name Trophinin Associated Protein Molecular Type Protein
Molecular Formula Molecular Weight Core Functional Dimensions Prognosis (cytogenetically normal AML)
Disease Acute Myeloid Leukemia (AML) Disease Subtypes /
Organ Blood, bone marrow Test Sample / Technology Platform Bone marrow (RNA sequencing, qRT-PCR)
Pathobiological Mechanisms High expression is associated with chemosensitivity, while low expression is observed in leukemia stem cells.
Clinical Availability Status Research validation: Can serve as an independent prognostic predictor for CN-AML.
Notes and Dynamics The expression level is associated with drug susceptibility to multiple agents, guiding the selection of chemotherapy regimens.

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This study was supported by the Scientific Research Innovation Capability Support Project for Young Faculty (SRICSPYF-ZY2025112), the Fundamental and Interdisciplinary Disciplines Breakthrough Plan of the Ministry of Education of China (JYB2025XDXM612)

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