Parameter
| Biomarker | circZBTB46 | Full name | Circular Zinc Finger And BTB Domain Containing 46 | Molecular Type | Nucleic acid (circRNA) |
|---|---|---|---|---|---|
| Molecular Formula | Molecular Weight | Core Functional Dimensions | Diagnosis, prognosis, therapeutic targets | ||
| Disease | Acute Myeloid Leukemia (AML) | Disease Subtypes | / | ||
| Organ | Blood, bone marrow | Test Sample / Technology Platform | Bone marrow/AML cell lines (qRT-PCR, RNA sequencing) | ||
| Pathobiological Mechanisms | As a miRNA sponge, it upregulates SCD expression and protects AML cells from ferroptosis | ||||
| Clinical Availability Status | Cutting-edge Research: Demonstrates high sensitivity and specificity for AML diagnosis. | ||||
| Notes and Dynamics | Associated with ferroptosis, combination with ferroptosis inducers may enhance therapeutic efficacy. | ||||