Parameter
| Biomarker | DPP4 | Full name | Dipeptidyl Peptidase 4 | Molecular Type | Protein |
|---|---|---|---|---|---|
| Molecular Formula | Molecular Weight | Core Functional Dimensions | Diagnosis, prognosis, drug resistance-related | ||
| Disease | Acute Myeloid Leukemia (AML) | Disease Subtypes | / | ||
| Organ | Blood, bone marrow | Test Sample / Technology Platform | Bone marrow (RNA sequencing, qRT-PCR) | ||
| Pathobiological Mechanisms | Expression dysregulation affects chemotherapy sensitivity and participates in ferroptosis-related pathway regulation. | ||||
| Clinical Availability Status | Research validation: Incorporating the FRG prognostic model, the 1-5 year AUC value demonstrates predictive validity. | ||||
| Notes and Dynamics | Significantly downregulated in AML samples, closely associated with chemotherapy resistance. | ||||