Parameter
| Biomarker | TFRC | Full name | Transferrin Receptor 1 | Molecular Type | Protein |
|---|---|---|---|---|---|
| Molecular Formula | Molecular Weight | Core Functional Dimensions | Diagnosis, prognosis, drug resistance-related | ||
| Disease | Acute Myeloid Leukemia (AML) | Disease Subtypes | / | ||
| Organ | Blood, bone marrow | Test Sample / Technology Platform | Bone marrow (RNA sequencing, qRT-PCR) | ||
| Pathobiological Mechanisms | Participates in iron metabolism, with abnormal expression affecting leukemia cell survival and chemotherapeutic response | ||||
| Clinical Availability Status | Research validation: As a prognostic marker, it works synergistically with DPP4. | ||||
| Notes and Dynamics | Upregulated in AML samples, its expression level can guide the selection of chemotherapy regimens. | ||||