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160

Parameter
Biomarker 5-MTP Full name 5-Methoxytryptophan Molecular Type Metabolites
Molecular Formula C₁₂H₁₄N₂O₃ Molecular Weight 234.25 g/mol Core Functional Dimensions Early screening, Risk stratification
Disease Chronic Kidney Disease (CKD) Disease Subtypes /
Organ Kidney Test Sample / Technology Platform Urine ( mass spectrometry, proteomics detection )
Pathobiological Mechanisms Regulating inflammation and fibrosis pathways, abnormal levels are associated with CKD progression
Clinical Availability Status Research verification stage
Notes and Dynamics Inhibiting NF-κB pathway can improve CKD-induced cerebrovascular injury, which has the potential of biomarkers and therapeutic targets.

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This study was supported by the Scientific Research Innovation Capability Support Project for Young Faculty (SRICSPYF-ZY2025112), the Fundamental and Interdisciplinary Disciplines Breakthrough Plan of the Ministry of Education of China (JYB2025XDXM612)

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