Parameter
| Biomarker | LOC541471 | Full name | Long Intergenic Non-Protein Coding RNA 541471 | Molecular Type | Nucleic acid (lncRNA) |
|---|---|---|---|---|---|
| Molecular Formula | Molecular Weight | Core Functional Dimensions | Prognosis, risk stratification | ||
| Disease | Acute Myeloid Leukemia (AML) | Disease Subtypes | / | ||
| Organ | Blood, bone marrow | Test Sample / Technology Platform | Bone marrow (RNA sequencing, siRNA validation) | ||
| Pathobiological Mechanisms | High expression inhibits apoptosis and promotes proliferation, incorporated into the risk score model of the line graph | ||||
| Clinical Availability Status | Research Verification: TCGA Data + 52 clinical samples for validation. | ||||
| Notes and Dynamics | The risk stratification model constructed in combination with GDAP1, SOD1, and STK25 demonstrated high predictive accuracy. | ||||