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29

Parameter
Biomarker GDAP1 Full name Ganglioside Induced Differentiation-Associated Protein 1 Molecular Type Protein
Molecular Formula Molecular Weight Core Functional Dimensions Prognosis, risk stratification
Disease Acute Myeloid Leukemia (AML) Disease Subtypes /
Organ Blood, bone marrow Test Sample / Technology Platform Bone marrow (RNA sequencing, siRNA validation)
Pathobiological Mechanisms It contributes the most to overall survival, with high expression associated with poor prognosis.
Clinical Availability Status Research validation: Knockdown promotes apoptosis of THP-1 cells.
Notes and Dynamics One of the core prognostic factors in the line chart model.

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This study was supported by the Scientific Research Innovation Capability Support Project for Young Faculty (SRICSPYF-ZY2025112), the Fundamental and Interdisciplinary Disciplines Breakthrough Plan of the Ministry of Education of China (JYB2025XDXM612)

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