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Parameter
Biomarker SOD1 Full name Superoxide Dismutase 1 Molecular Type Protein
Molecular Formula Molecular Weight Core Functional Dimensions Prognosis, risk stratification
Disease Acute Myeloid Leukemia (AML) Disease Subtypes /
Organ Blood, bone marrow Test Sample / Technology Platform Bone marrow (RNA sequencing, siRNA validation)
Pathobiological Mechanisms High expression is involved in the proliferation regulation of AML cells and associated with disease progression.
Clinical Availability Status Research validation: Enhanced risk stratification accuracy when combined with the other three factors.
Notes and Dynamics Targeted inhibition can serve as one of the combination therapy strategies.

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This study was supported by the Scientific Research Innovation Capability Support Project for Young Faculty (SRICSPYF-ZY2025112), the Fundamental and Interdisciplinary Disciplines Breakthrough Plan of the Ministry of Education of China (JYB2025XDXM612)

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