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Parameter
Biomarker LRP12 Full name Low Density Lipoprotein Receptor-Related Protein 12 Molecular Type Protein
Molecular Formula Molecular Weight Core Functional Dimensions Diagnosis
Disease Acute Myeloid Leukemia (AML) Disease Subtypes /
Organ Blood, bone marrow Test Sample / Technology Platform Bone marrow/AML cell line (RNA sequencing, in vitro validation).
Pathobiological Mechanisms Co-overexpression with CD109, associated with immune checkpoint molecule dysregulation, promotes cancer cell immune evasion.
Clinical Availability Status Research Verification: Secretome analysis confirms its expression profile.
Notes and Dynamics First reported as a biomarker related to AML diagnosis.

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This study was supported by the Scientific Research Innovation Capability Support Project for Young Faculty (SRICSPYF-ZY2025112), the Fundamental and Interdisciplinary Disciplines Breakthrough Plan of the Ministry of Education of China (JYB2025XDXM612)

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