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34

Parameter
Biomarker WT1 Full name Wilms Tumor 1 Molecular Type Protein
Molecular Formula Molecular Weight Core Functional Dimensions Diagnosis, prognosis, and treatment response monitoring
Disease Acute Myeloid Leukemia (AML) Disease Subtypes /
Organ Blood, bone marrow Test Sample / Technology Platform Bone marrow/blood (RNA sequencing, qPCR)
Pathobiological Mechanisms Overexpression is associated with elevated white blood cell count and increased proportion of primitive cells, with expression levels decreasing after induction therapy.
Clinical Availability Status Clinical validation: 345 diagnostic samples confirm its value.
Notes and Dynamics Can monitor disease status and guide risk stratification and treatment decisions.

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This study was supported by the Scientific Research Innovation Capability Support Project for Young Faculty (SRICSPYF-ZY2025112), the Fundamental and Interdisciplinary Disciplines Breakthrough Plan of the Ministry of Education of China (JYB2025XDXM612)

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