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36

Parameter
Biomarker CXCL-12 Full name C-X-C Motif Chemokine Ligand 12 Molecular Type Protein
Molecular Formula Molecular Weight Core Functional Dimensions Prognosis, monitoring
Disease Acute Myeloid Leukemia (AML) Disease Subtypes /
Organ Blood, bone marrow Test Sample / Technology Platform Bone marrow plasma (ELISA)
Pathobiological Mechanisms Down-regulated during diagnosis, up-regulated after complete remission and relapse, reflecting changes in the bone marrow microenvironment.
Clinical Availability Status Research validation: Inverse correlation with Activin-A expression.
Notes and Dynamics As an auxiliary biomarker for disease progression monitoring.

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This study was supported by the Scientific Research Innovation Capability Support Project for Young Faculty (SRICSPYF-ZY2025112), the Fundamental and Interdisciplinary Disciplines Breakthrough Plan of the Ministry of Education of China (JYB2025XDXM612)

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