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Parameter
Biomarker Vitamin B12 Full name Cobalamin Molecular Type Vitamin
Molecular Formula C63H88CoN14O14P Molecular Weight 1355.365 Core Functional Dimensions Diagnosis, etiological differentiation
Disease Anemia Disease Subtypes /
Organ Blood, bone marrow Test Sample / Technology Platform Serum (chemiluminescence method, radioimmunoassay)
Pathobiological Mechanisms Involved in DNA synthesis, deficiency leads to megaloblastic change of bone marrow hematopoietic cells, red blood cell maturation disorders.
Clinical Availability Status Clinical routine application: Key indicators for diagnosing megaloblastic anemia.
Notes and Dynamics It can be combined with the levels of homocysteine and methylmalonic acid to improve the diagnostic accuracy.

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This study was supported by the Scientific Research Innovation Capability Support Project for Young Faculty (SRICSPYF-ZY2025112), the Fundamental and Interdisciplinary Disciplines Breakthrough Plan of the Ministry of Education of China (JYB2025XDXM612)

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