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Parameter
Biomarker Folic acid Full name Folic acid Molecular Type Vitamin
Molecular Formula C19H19N7O6 Molecular Weight 441.397 Core Functional Dimensions Diagnosis, etiological differentiation
Disease Anemia Disease Subtypes /
Organ Blood, bone marrow Test Sample / Technology Platform Serum/Red blood cells (chemiluminescence method, microbial method)
Pathobiological Mechanisms Involved in DNA synthesis, deficiency leads to erythropoiesis disorders, megaloblastic changes.
Clinical Availability Status Clinical routine application: Core indicators for classification of megaloblastic anemia.
Notes and Dynamics Red blood cell folate can better reflect long-term folate reserves and is superior to serum folate testing.

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This study was supported by the Scientific Research Innovation Capability Support Project for Young Faculty (SRICSPYF-ZY2025112), the Fundamental and Interdisciplinary Disciplines Breakthrough Plan of the Ministry of Education of China (JYB2025XDXM612)

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