Parameter
| Biomarker | EASIX | Full name | Endothelial Activation and Stress Index (calculated as sVCAM-1×creatinine/platelet count) | Molecular Type | Composite index |
|---|---|---|---|---|---|
| Molecular Formula | Molecular Weight | Core Functional Dimensions | Prognosis, risk stratification | ||
| Disease | Anemia | Disease Subtypes | / | ||
| Organ | Blood, bone marrow | Test Sample / Technology Platform | Based on clinical detection parameters (such as creatinine, bilirubin, etc.) for calculation | ||
| Pathobiological Mechanisms | It is associated with endothelial dysfunction in patients with anemia and predicts all-cause mortality. | ||||
| Clinical Availability Status | National cohort validation: 2954 patients were followed up for 81 months. | ||||
| Notes and Dynamics | Critical value: 0.72. The hazard ratio for all-cause mortality in the high-score group was 1.42, and the 10-year predicted area under the curve was 0.78. | ||||