Parameter
| Biomarker | miR-451 | Full name | MicroRNA-451 | Molecular Type | Nucleic acid（non-coding RNA） |
|---|---|---|---|---|---|
| Molecular Formula | / | Molecular Weight | / | Core Functional Dimensions | Early prediction、Condition monitoring |
| Disease | Chronic Kidney Disease (CKD) | Disease Subtypes | / | ||
| Organ | Kidney | Test Sample / Technology Platform | Urine, plasma (RNA sequencing, quantitative PCR) | ||
| Pathobiological Mechanisms | Post-transcriptional regulation of kidney injury-related genes, abnormal plasma / urine levels in CKD | ||||
| Clinical Availability Status | Research verification stage | ||||
| Notes and Dynamics | The sensitivity of plasma and urine miR-451 in the diagnosis of diabetic nephropathy was 90.9 % and 95.5 %, respectively. | ||||