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Parameter
Biomarker miR-181a Full name MicroRNA-181a Molecular Type Nucleic acid(non-coding RNA)
Molecular Formula / Molecular Weight / Core Functional Dimensions Early prediction、Condition monitoring
Disease Chronic Kidney Disease (CKD) Disease Subtypes /
Organ Kidney Test Sample / Technology Platform Urine, plasma (RNA sequencing, quantitative PCR)
Pathobiological Mechanisms Regulating renal parenchymal injury-related genes, the level of urinary exosomes in CKD patients was significantly reduced.
Clinical Availability Status Research verification stage
Notes and Dynamics The level of miR-181a in urinary exosomes of CKD patients is about 200 times lower than that of healthy people, which is a highly specific marker of renal parenchymal injury.

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This study was supported by the Scientific Research Innovation Capability Support Project for Young Faculty (SRICSPYF-ZY2025112), the Fundamental and Interdisciplinary Disciplines Breakthrough Plan of the Ministry of Education of China (JYB2025XDXM612)

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