Parameter
| Biomarker | miR-181a | Full name | MicroRNA-181a | Molecular Type | Nucleic acid(non-coding RNA) |
|---|---|---|---|---|---|
| Molecular Formula | / | Molecular Weight | / | Core Functional Dimensions | Early prediction、Condition monitoring |
| Disease | Chronic Kidney Disease (CKD) | Disease Subtypes | / | ||
| Organ | Kidney | Test Sample / Technology Platform | Urine, plasma (RNA sequencing, quantitative PCR) | ||
| Pathobiological Mechanisms | Regulating renal parenchymal injury-related genes, the level of urinary exosomes in CKD patients was significantly reduced. | ||||
| Clinical Availability Status | Research verification stage | ||||
| Notes and Dynamics | The level of miR-181a in urinary exosomes of CKD patients is about 200 times lower than that of healthy people, which is a highly specific marker of renal parenchymal injury. | ||||