Parameter
| Biomarker | TGF-β1、miRNA-21-5p、miR-21 | Full name | Transforming growth factor-beta 1、MicroRNA-21-5p、MicroRNA-21 | Molecular Type | Protein、RNA（miRNA） |
|---|---|---|---|---|---|
| Molecular Formula | / | Molecular Weight | / | Core Functional Dimensions | Assessment and prognosis of renal fibrosis |
| Disease | Glomerulonephritis (GN) | Disease Subtypes | / | ||
| Organ | Kidney | Test Sample / Technology Platform | Blood | ||
| Pathobiological Mechanisms | TGF-β1 is a pro-fibrotic molecule, and miR-21 is associated with renal fibrosis. Both are associated with the degree of renal fibrosis and renal outcome in IgAN. | ||||
| Clinical Availability Status | Research verification stage：For non-invasive evaluation of renal fibrosis, clinical transformation verification is required | ||||
| Notes and Dynamics | Notes and dynamics It can replace some invasive renal biopsy to evaluate the risk of renal fibrosis in patients with IgAN and guide anti-fibrosis treatment. | ||||