Parameter
| Biomarker | MASP2 | Full name | Mannan-binding lectin-associated serine protease 2 | Molecular Type | Protein |
|---|---|---|---|---|---|
| Molecular Formula | / | Molecular Weight | / | Core Functional Dimensions | Severity assessment and prognosis of renal injury |
| Disease | Glomerulonephritis (GN) | Disease Subtypes | / | ||
| Organ | Kidney | Test Sample / Technology Platform | Urinary extracellular vesicles | ||
| Pathobiological Mechanisms | Involved in the mannan-binding lectin pathway, the level of MASP2 in UEV is related to IgAN, reflecting the degree of renal injury. | ||||
| Clinical Availability Status | Research verification stage：It is related to the prognosis of IgAN, which needs to be verified by a larger sample size. | ||||
| Notes and Dynamics | It provides a new direction for the study of the mechanism of IgAN renal injury. The characteristics of UEV carrier may improve the specificity of marker detection. | ||||