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176

Parameter
Biomarker Escherichia-Shigella Full name Escherichia-Shigella Molecular Type Microorganism
Molecular Formula / Molecular Weight / Core Functional Dimensions Diagnosis and pathogenesis are related
Disease Glomerulonephritis (GN) Disease Subtypes /
Organ Kidney Test Sample / Technology Platform Flora samples ( no specific technology )
Pathobiological Mechanisms Intestinal flora imbalance and significant expansion of Escherichia-Shigella in IgAN patients may be involved in the pathogenesis of IgAN.
Clinical Availability Status Research and exploration stage : It is related to IgAN attack and treatment response, which needs mechanism and clinical verification.
Notes and Dynamics It provides a basis for the study of the mechanism of IgAN ' intestine-kidney axis ', and may improve the condition of IgAN by regulating intestinal flora.

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This study was supported by the Scientific Research Innovation Capability Support Project for Young Faculty (SRICSPYF-ZY2025112), the Fundamental and Interdisciplinary Disciplines Breakthrough Plan of the Ministry of Education of China (JYB2025XDXM612)

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