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179

Parameter
Biomarker sIL-2Rα Full name Serum soluble interleukin-2 receptor α Molecular Type Protein
Molecular Formula / Molecular Weight / Core Functional Dimensions Histological injury assessment and prognosis
Disease Glomerulonephritis (GN) Disease Subtypes /
Organ Kidney Test Sample / Technology Platform Serum
Pathobiological Mechanisms It is associated with severe inflammatory cell infiltration in IgAN, which can predict the short-term progression of the disease and reflect the degree of histological damage.
Clinical Availability Status Research verification stage : Non-invasive assessment of histological damage requires clinical application verification.
Notes and Dynamics It can avoid partial renal biopsy and provide a non-invasive method for evaluating the degree of inflammation and prognosis of IgAN.

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This study was supported by the Scientific Research Innovation Capability Support Project for Young Faculty (SRICSPYF-ZY2025112), the Fundamental and Interdisciplinary Disciplines Breakthrough Plan of the Ministry of Education of China (JYB2025XDXM612)

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