Parameter
| Biomarker | KMN scheme based on k-means clustering | Full name | Network biomarkers ( KMN scheme based on k-means clustering ) | Molecular Type | Multimolecular integration |
|---|---|---|---|---|---|
| Molecular Formula | / | Molecular Weight | / | Core Functional Dimensions | Risk stratification, treatment guidance |
| Disease | Glomerulonephritis (GN) | Disease Subtypes | / | ||
| Organ | Kidney | Test Sample / Technology Platform | Multi-dimensional data ( network analysis, clustering algorithm ) | ||
| Pathobiological Mechanisms | Combining network biomarkers with unsupervised learning to improve the risk stratification of IgAN and make up for the deficiency of traditional models that only rely on renal indicators. | ||||
| Clinical Availability Status | Research verification stage : KMN protocol is effective and needs to be verified by clinical practice. | ||||
| Notes and Dynamics | It is a new paradigm for the application of biomarkers to achieve refined risk assessment of IgAN and provide decision support for individualized treatment. | ||||