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181

Parameter
Biomarker uNAG Full name Urinary N-acetyl-β-D-glucosaminidase Molecular Type Enzyme(Protein)
Molecular Formula / Molecular Weight / Core Functional Dimensions Renal tubulointerstitial injury assessment and remission prediction
Disease Glomerulonephritis (GN) Disease Subtypes /
Organ Kidney Test Sample / Technology Platform Urine
Pathobiological Mechanisms It is released by the damaged proximal renal tubular epithelial cells, reflecting renal tubular interstitial involvement, and can predict the remission status of IgAN.
Clinical Availability Status Research verification stage : It is related to the remission of IgAN and needs to be verified by clinical promotion.
Notes and Dynamics It is an important non-invasive marker for evaluating renal tubulointerstitial injury and therapeutic effect of IgAN.

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This study was supported by the Scientific Research Innovation Capability Support Project for Young Faculty (SRICSPYF-ZY2025112), the Fundamental and Interdisciplinary Disciplines Breakthrough Plan of the Ministry of Education of China (JYB2025XDXM612)

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