Parameter
| Biomarker | Urinary complement protein ( involving AP, LP pathway ) | Full name | Urinary complement proteins (alternative pathway, lectin pathway) | Molecular Type | Protein |
|---|---|---|---|---|---|
| Molecular Formula | / | Molecular Weight | / | Core Functional Dimensions | Disease progression assessment |
| Disease | Glomerulonephritis (GN) | Disease Subtypes | / | ||
| Organ | Kidney | Test Sample / Technology Platform | Urine ( Quantitative Proteinomics ) | ||
| Pathobiological Mechanisms | Urine complement protein was enriched in IgAN patients, suggesting that complement alternative pathway ( AP ) and lectin pathway ( LP ) were activated and involved in the progression of IgAN | ||||
| Clinical Availability Status | Research verification stage : It is related to the progression of IgAN and needs to be verified by complement pathway mechanism. | ||||
| Notes and Dynamics | To reveal the role of complement system in IgAN, and provide a basis for targeted complement therapy for IgAN. | ||||