Parameter
| Biomarker | SNUPE、eSNGFR | Full name | Single Nephron Ultrafiltration Parameters、estimated Single Nephron Glomerular Filtration Rate | Molecular Type | Physiological parameters |
|---|---|---|---|---|---|
| Molecular Formula | / | Molecular Weight | / | Core Functional Dimensions | Renal function assessment, disease progression monitoring |
| Disease | Glomerulonephritis (GN) | Disease Subtypes | / | ||
| Organ | Kidney | Test Sample / Technology Platform | Not clear ( functional assessment ) | ||
| Pathobiological Mechanisms | SNUPE is a sensitive biomarker, and eSNGFR cannot increase compensatoryly with the decrease of functional nephrons, reflecting the compensatory ability of diseased glomeruli. | ||||
| Clinical Availability Status | Research verification stage: It is necessary to standardize clinical detection to reflect glomerular compensatory function. | ||||
| Notes and Dynamics | To evaluate the renal reserve capacity of IgAN from the functional point of view, and to provide a basis for judging the stage of disease progression. | ||||