Parameter
| Biomarker | u-sCD163 | Full name | Urinary soluble CD163 | Molecular Type | Protein |
|---|---|---|---|---|---|
| Molecular Formula | / | Molecular Weight | / | Core Functional Dimensions | Disease severity assessment and remission status prediction |
| Disease | Glomerulonephritis (GN) | Disease Subtypes | / | ||
| Organ | Kidney | Test Sample / Technology Platform | Urine（ELISA） | ||
| Pathobiological Mechanisms | he shedding of monocytes and macrophages is related to the excessive activation of macrophages. The level of u-sCD163 is related to the histopathological activity, clinical manifestations and remission status of IgAN. | ||||
| Clinical Availability Status | Research verification stage：Non-invasive assessment of disease status requires large sample verification. | ||||
| Notes and Dynamics | It can be used as an important non-invasive index for disease monitoring and efficacy evaluation of IgAN patients, and is highly correlated with disease activity. | ||||