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189

Parameter
Biomarker Urine IL-6、TGF-β1 Full name Urinary interleukin-6、Urinary transforming growth factor-beta 1 Molecular Type Protein
Molecular Formula / Molecular Weight / Core Functional Dimensions Disease progression prediction
Disease Glomerulonephritis (GN) Disease Subtypes /
Organ Kidney Test Sample / Technology Platform Urine
Pathobiological Mechanisms Elevated levels of urinary IL-6 and TGF-β1 are associated with an increased risk of IgAN progression, and urinary IL-6 is an independent risk factor for IgAN progression.
Clinical Availability Status Research verification stage:The predictive value is clear and needs to be verified by clinical application.
Notes and Dynamics It provides an important basis for the prognostic stratification of IgAN and can guide the timing of clinical intervention.

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This study was supported by the Scientific Research Innovation Capability Support Project for Young Faculty (SRICSPYF-ZY2025112), the Fundamental and Interdisciplinary Disciplines Breakthrough Plan of the Ministry of Education of China (JYB2025XDXM612)

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