Parameter
| Biomarker | mtDNA / nDNA)/ nucleosome | Full name | Mitochondrial DNA / nuclear DNA )/ nucleosome | Molecular Type | Nucleic Acid/ Nucleic Acid Protein Complex |
|---|---|---|---|---|---|
| Molecular Formula | / | Molecular Weight | / | Core Functional Dimensions | Early diagnosis、Tissue injury assessment |
| Disease | Acute Kidney Injury (AKI) | Disease Subtypes | / | ||
| Organ | Kidney | Test Sample / Technology Platform | Plasma（PCR、ELISA） | ||
| Pathobiological Mechanisms | The damage-associated molecular pattern ( DAMP ) released during cell necrosis reflects systemic and renal cell injury. | ||||
| Clinical Availability Status | Study test | ||||
| Notes and Dynamics | The high level of admission predicts post-traumatic AKI, and nDNA can be used as an early intervention target. | ||||