Parameter
| Biomarker | Neurofilament light Chain (NfL) | Full name | Neurofilament light polypeptide | Molecular Type | Protein |
|---|---|---|---|---|---|
| Molecular Formula | Molecular Weight | Core Functional Dimensions | Monitoring, prognosis | ||
| Disease | Liver Cirrhosis | Disease Subtypes | / | ||
| Organ | Liver | Test Sample / Technology Platform | CSF/Plasma (SIMOA) | ||
| Pathobiological Mechanisms | Cytoskeletal proteins released after axonal injury are nonspecific markers of neuronal injury. | ||||
| Clinical Availability Status | Research/clinical monitoring tools: widely used in clinical trials for effectiveness monitoring indicators; It is used clinically to evaluate the overall progress of neurodegenerative diseases. | ||||
| Notes and Dynamics | It is elevated in a variety of diseases such as AD, MS, ALS, and is used to evaluate disease activity and treatment response. | ||||