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1008

Parameter
Biomarker GFAP Full name Glial fibrillary acidic protein Molecular Type Protein
Molecular Formula Molecular Weight Core Functional Dimensions Susceptibility, early diagnosis
Disease Liver Cirrhosis Disease Subtypes /
Organ Liver Test Sample / Technology Platform Plasma (SIMOA)
Pathobiological Mechanisms A sign of astrocyte activation. In AD, they may be activated early in the pathological response to Aβ.
Clinical Availability Status Frontier research: a large amount of evidence shows that it changes in the presymptomatic stage and is a potential risk warning marker.
Notes and Dynamics It is highly correlated with Aβ pathology and may reflect changes in the brain earlier than p-tau.

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This study was supported by the Scientific Research Innovation Capability Support Project for Young Faculty (SRICSPYF-ZY2025112), the Fundamental and Interdisciplinary Disciplines Breakthrough Plan of the Ministry of Education of China (JYB2025XDXM612)

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