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1009

Parameter
Biomarker APOE ε4 Full name Apolipoprotein Eε4 allele Molecular Type Nucleic acid (DNA)
Molecular Formula Molecular Weight Core Functional Dimensions Susceptibility
Disease Liver Cirrhosis Disease Subtypes /
Organ Liver Test Sample / Technology Platform Whole blood (genotyping)
Pathobiological Mechanisms Influence of lipid metabolism, especially related to cleared A beta efficiency is lower, carried A beta risk and time in advance.
Clinical Availability Status Clinical available (risk assessment) : conventional genetic tests available, but only for risk assessment, is not used for diagnosis. Important ethical issues are involved.
Notes and Dynamics It is the core variable of establishing risk stratification model; It is also an important stratification factor in treatment trials.

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This study was supported by the Scientific Research Innovation Capability Support Project for Young Faculty (SRICSPYF-ZY2025112), the Fundamental and Interdisciplinary Disciplines Breakthrough Plan of the Ministry of Education of China (JYB2025XDXM612)

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