Parameter
| Biomarker | BRAF | Full name | B-Raf proto-oncogene, serine/threonine kinase | Molecular Type | Nucleic acid (DNA) |
|---|---|---|---|---|---|
| Molecular Formula | Molecular Weight | 95 kDa | Core Functional Dimensions | Targets for Treatment | |
| Disease | Angiosarcoma | Disease Subtypes | / | ||
| Organ | All cells (MAPK pathway) | Test Sample / Technology Platform | Organization (NGS, WES, WGS) | ||
| Pathobiological Mechanisms | Mutations activate the MAPK/ERK pathway, enhance cell proliferation and tumor | ||||
| Clinical Availability Status | Validation: rare but function key | ||||
| Notes and Dynamics | Mutations are hot spot mutations, MEK inhibitors may have a potential treatment | ||||