Parameter
| Biomarker | KHDRBS1::NTRK3 fusion gene | Full name | KH domain containing, RNA binding, signal transduction associated 1::Neurotrophic receptor tyrosine kinase 3 gene fusion | Molecular Type | Nucleic acid (RNA/DNA) |
|---|---|---|---|---|---|
| Molecular Formula | Molecular Weight | 180-220 kDa | Core Functional Dimensions | Therapeutic targets | |
| Disease | Angiosarcoma | Disease Subtypes | / | ||
| Organ | Tumor cells (vascular endothelial origin) | Test Sample / Technology Platform | Organization (NGS, RNA sequencing) | ||
| Pathobiological Mechanisms | Activate the TRK signaling pathways, and promote the tumor cell proliferation and survival | ||||
| Clinical Availability Status | Cutting-edge research: AS found in children | ||||
| Notes and Dynamics | To la rochelle for (TRK inhibitors) have complete and lasting response | ||||