Parameter
| Biomarker | VEGF-C / VEGF-D | Full name | Vascular endothelial growth factor C / Vascular endothelial growth factor D | Molecular Type | protein |
|---|---|---|---|---|---|
| Molecular Formula | Molecular Weight | VEGF-C: 40 kDa; VEGF-D: 45 kDa | Core Functional Dimensions | Therapeutic targets, prognosis | |
| Disease | Angiosarcoma | Disease Subtypes | / | ||
| Organ | Tumor cells, stromal cells | Test Sample / Technology Platform | Tissue/serum (IHC, ELISA) | ||
| Pathobiological Mechanisms | Lymph angiogenesis regulation, the promotion of tumor lymphatic metastasis | ||||
| Clinical Availability Status | Validation: late subtypes enrichment | ||||
| Notes and Dynamics | The expression of VEGF-C was heterogeneous (12%-88%), and the serum level of VEGF-D increased with the stage | ||||