Parameter
| Biomarker | ANG1 / ANG2 | Full name | Angiopoietin 1 / Angiopoietin 2 | Molecular Type | protein |
|---|---|---|---|---|---|
| Molecular Formula | Molecular Weight | ANG1:55 kDa; ANG2:55 kDa | Core Functional Dimensions | Prognosis, therapeutic targets | |
| Disease | Angiosarcoma | Disease Subtypes | / | ||
| Organ | Tumor cells, stromal cells | Test Sample / Technology Platform | Organization/serum (IHC, ELISA) | ||
| Pathobiological Mechanisms | Regulation ANGPT-TIE pathway, ANG1 to maintain stable blood vessels, ANG2 promote vascular remodeling | ||||
| Clinical Availability Status | ANG2 was identified as a potential target | ||||
| Notes and Dynamics | The high expression of ANG1 is associated with a good prognosis, and the serum level of ANG2 is increased in advanced AS | ||||