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838

Parameter
Biomarker PAI-1 Full name Plasminogen activator inhibitor-1 Molecular Type Protein
Molecular Formula Molecular Weight 43 kDa Core Functional Dimensions Prognosis, therapeutic targets
Disease Angiosarcoma Disease Subtypes /
Organ Tumor cells, endothelial cells, hepatocytes Test Sample / Technology Platform Organization/serum (IHC, ELISA)
Pathobiological Mechanisms Promote angiogenesis, immune suppression and tumor microenvironment remodeling
Clinical Availability Status Cutting-edge research: inhibitors in clinical trials
Notes and Dynamics And SASP factor synergy, TM5614 joint nivolumab in resistance against PD-1 AS effective

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This study was supported by the Scientific Research Innovation Capability Support Project for Young Faculty (SRICSPYF-ZY2025112), the Fundamental and Interdisciplinary Disciplines Breakthrough Plan of the Ministry of Education of China (JYB2025XDXM612)

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