Parameter
| Biomarker | PD-L1 | Full name | Programmed death-ligand 1 | Molecular Type | Protein |
|---|---|---|---|---|---|
| Molecular Formula | Molecular Weight | 33 kDa | Core Functional Dimensions | Therapeutic targets, and prognosis | |
| Disease | Angiosarcoma | Disease Subtypes | / | ||
| Organ | Tumor cells, immune cells | Test Sample / Technology Platform | Organization (IHC) | ||
| Pathobiological Mechanisms | The tumor cell surface molecules, inhibit T cell activity, mediated immune escape | ||||
| Clinical Availability Status | Clinical validation: predictive markers for ICIs treatment | ||||
| Notes and Dynamics | The expression is heterogeneous, which is related to CD8+ T cell infiltration, and the patients with high expression are more sensitive to ICIs | ||||