Parameter
| Biomarker | miR-497 / miR-497-5p | Full name | MicroRNA-497 / MicroRNA-497-5p | Molecular Type | Nucleic acid (RNA) |
|---|---|---|---|---|---|
| Molecular Formula | Molecular Weight | 6.6 kDa | Core Functional Dimensions | Therapeutic targets | |
| Disease | Angiosarcoma | Disease Subtypes | / | ||
| Organ | Tumor cells | Test Sample / Technology Platform | Tissue/serum (qRT-PCR, NGS) | ||
| Pathobiological Mechanisms | Tumor suppressor miRNA targeting CCND2, CDK6, KCa3.1 and other genes | ||||
| Clinical Availability Status | Study validation: Multi-target regulation | ||||
| Notes and Dynamics | Overexpression reduced tumor cell migration and formation, while miR-497-5p inhibited cell proliferation and invasion | ||||