Parameter
| Biomarker | pks+ E. coli | Full name | Polyketide synthase-positive Escherichia coli | Molecular Type | Bacteria |
|---|---|---|---|---|---|
| Molecular Formula | Molecular Weight | Core Functional Dimensions | Diagnosis, susceptibility | ||
| Disease | Colorectal Cancer (CRC) | Disease Subtypes | / | ||
| Organ | Colorectal | Test Sample / Technology Platform | Tumor tissue/stool (qPCR, metagenomic sequencing) | ||
| Pathobiological Mechanisms | Colicin production leads to DNA double-strand breaks and genomic instability, promoting tumorigenesis | ||||
| Clinical Availability Status | Research validation: The enrichment phenomenon has been verified in clinical samples and has not entered routine clinical application | ||||
| Notes and Dynamics | Colistin damage characteristics can be used as a molecular fingerprint for early diagnosis of CRC, and combined detection with Fn can improve the diagnostic accuracy | ||||