Parameter
| Biomarker | Clostridium symbiosum (C. symbiosum) | Full name | Clostridium symbiosum | Molecular Type | Bacteria |
|---|---|---|---|---|---|
| Molecular Formula | Molecular Weight | Core Functional Dimensions | Diagnosis, Prognosis | ||
| Disease | Colorectal Cancer (CRC) | Disease Subtypes | / | ||
| Organ | Colorectal | Test Sample / Technology Platform | Stool/tumor tissue (qPCR, metagenomic sequencing) | ||
| Pathobiological Mechanisms | The production of branched-chain amino acids activates the mTORC1 pathway, which promotes cholesterol synthesis and cancer stem cell properties | ||||
| Clinical Availability Status | Study validation: Stool test showed diagnostic value and was in the stage of clinical transformation research | ||||
| Notes and Dynamics | Its abundance gradually increases with the adenoma-carcinoma sequence, which can be used as a non-invasive early diagnostic marker. Combined with FIT, it can improve the screening sensitivity | ||||